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Experience with conventional dialysis in The Centre Cancer Dharmais Hospital, Jakarta, Indonesia

Imam Effendi *, Abidin Wijanarko ** Hardina Sabrida***
*Division of Nephrology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
**Division Hematology
***Unit of Dialysis Centre Cancer Dharmais Hospital, Jakarta, Indonesia

 

Background
Cancer is associated with patient weakness and severe illness because the metastatic diseasesis and loss of appetite. The nephrological complications include renal failure (ARF, Acute on chronic ARF or CKD). In the past hemodialysis was a relative contra indication for cancer sufferers especially those with metastic disease. Nowadays hemodialysis is used for other indications: drug dosing and improving the quality of life before death.
The aim of this study is to evaluate the use of conventional hemodialysis (cHD) in terminal stages of cancer.

 

Methodse and Results
The cHD treatments were performed adjusted to individual patient requirements. There were 55 patients with cancer who were dialyzed; the most frequent diagnosis was obstructive nephropathy due to cervical cancer (> stage III (post obstructive)). Only 8 patients suffered nephrotoxic injury due to cisplatin or radiation. In these patients cHD was performed if the treatments with hydration and N acethyl cystein were incomplete and were aimed at increasing the renal function. The most common complication in the cancer patients were hypoalbuminemia (pre cHD) due to poor food intake or hypotension due to heart disease (pre or during cHD). Laboratory parameters : blood urea and serum creatinine levels were successfully decreased by the treatments but most of them increase again rapidly.
The most cHD treatments were performed 3 times with a maximum ofal 10 times before dieddeath..

 

Conclusion
cHD in terminal malignancy patients was observed to not prolong life and cHD clearly has limitations due to the poor general condition of the patients.

 

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